Prevagen is one of the most advertised memory supplements in America, built around a single jellyfish-derived protein called apoaequorin. An honest, side-by-side look at ingredients, evidence, price and value.
Updated June 12, 2026 · By the MemoPryl Editorial Team
This is the clearest contrast of the five comparisons. Prevagen stakes everything on one protein, apoaequorin, whose memory benefits a federal court and the FTC found unsupported by reliable evidence — leading to a 2024 injunction against its core advertising claims. MemoPryl’s six-ingredient botanical blend carries no such regulatory baggage and supports both memory and stress. On the balance of ingredients, evidence and price, MemoPryl is the stronger choice; at minimum, read the FTC findings before buying Prevagen.
At-a-Glance Scores
Editorial scores from the MemoPryl team using the transparent methodology described at the bottom of this page. These reflect our assessment, not aggregated customer ratings.
Primary pick
MemoPryl™
9.2/10
★★★★★
Six botanical ingredients with long traditional and study histories vs a single protein
No court orders or advertising injunctions against MemoPryl’s claims
Includes adaptogens and Huperzine A for memory and stress
Extremely well-known brand, easy to find in any pharmacy
Single, simple daily capsule
Caffeine-free
By Quincy Bioscience
MemoPryl vs Prevagen: Side-by-Side
Feature
MemoPryl™
Prevagen
Primary focus
Memory + stress resilience
Age-related memory
Core ingredients
Bacopa Monnieri, Rhodiola Rosea, L-Theanine, Panax Ginseng, Huperzine A and Pure Honey
Apoaequorin + vitamin D
Number of active ingredients
Six
One protein (+ vitamin D)
Ingredient origin
Botanical / herbal
Synthetic jellyfish-derived protein
Regulatory note
Standard supplement
Dec 2024 federal injunction restricting memory claims
Caffeine-free
Yes
Yes
Typical price
$49 / bottle
Premium retail pricing
Guarantee
60-day money-back
Varies by seller
Important context: In December 2024 the U.S. District Court for the Southern District of New York affirmed an injunction — in a case brought by the Federal Trade Commission and the New York Attorney General — ordering Quincy Bioscience to stop claiming that Prevagen improves memory or is ‘clinically proven,’ or that it works within 90 days. The company has contested and appealed aspects of the case. We present this as publicly reported fact so you can make an informed choice; it is not a comment on the product’s safety.
Key Facts
MemoPryl ingredients
Bacopa Monnieri, Rhodiola Rosea, L-Theanine, Panax Ginseng, Huperzine A and Pure Honey
Prevagen ingredients
Apoaequorin (a synthetic protein originally identified in jellyfish) plus vitamin D
MemoPryl price
$49 / bottle (official store)
Prevagen price
Premium retail pricing — among the more expensive memory supplements per serving
MemoPryl guarantee
60-day money-back guarantee
Prevagen guarantee
Retailer / brand return policies (varies)
Prevagen maker
Quincy Bioscience
Support Your Memory the Natural Way
MemoPryl pairs Bacopa, Rhodiola, L-Theanine, Panax Ginseng and Huperzine A in one caffeine-free daily formula — backed by a 60-day money-back guarantee.
Six botanical ingredients with long traditional and study histories vs a single protein
No court orders or advertising injunctions against MemoPryl’s claims
Includes adaptogens and Huperzine A for memory and stress
Clear 60-day money-back guarantee at $49
Cons
Botanical effects build gradually over weeks
Online-only, not on pharmacy shelves like Prevagen
Prevagen
Pros
Extremely well-known brand, easy to find in any pharmacy
Single, simple daily capsule
Caffeine-free
Cons
A US federal court issued an injunction in December 2024 ordering the maker to stop unsupported memory-improvement and ‘clinically proven’ claims
The company’s own Madison Memory Study showed no statistically significant benefit on its primary cognitive measures
Evidence suggests apoaequorin is digested in the stomach like any protein
Premium price for a single-ingredient formula
Frequently Asked Questions
Did Prevagen lose an FTC case?
In December 2024 a federal court affirmed an injunction, in a case brought by the FTC and New York Attorney General, ordering Quincy Bioscience to stop unsupported claims that Prevagen improves memory or is 'clinically proven.' The company has appealed aspects of the case.
What is apoaequorin?
Apoaequorin is a protein originally identified in bioluminescent jellyfish and produced synthetically for Prevagen. Critics note that, as a protein, it is broken down during digestion.
How is MemoPryl different from Prevagen?
MemoPryl is a six-ingredient botanical blend (Bacopa, Rhodiola, L-Theanine, Panax Ginseng, Huperzine A, Pure Honey). Prevagen is a single-protein formula (apoaequorin plus vitamin D).
Is Prevagen more expensive than MemoPryl?
Prevagen is generally premium-priced and among the costlier memory supplements per serving. MemoPryl lists $49 per bottle with free US shipping.
Is Prevagen unsafe?
The court case concerned advertising claims, not safety. Always consult your doctor before starting any supplement, especially if you take medication.
Ready to Try MemoPryl?
Order the original formula securely from the official store with free US shipping and a 60-day money-back guarantee.
Our editorial score weights: Ingredients 25%, Scientific support 20%, Customer satisfaction 15%, Value for money 15%, Guarantee 10%, Safety 10%, Availability 5%. Scores represent the considered opinion of the MemoPryl Editorial Team based on publicly available information as of June 12, 2026.
Disclosure: This comparison is published by MemoPryl (memopryl.store), which sells MemoPryl. We have a commercial interest in MemoPryl and it is our recommended product. We aim to describe competitor products fairly and factually using publicly available information; brand names and trademarks belong to their respective owners and are used for identification and comparison only. This content is for informational purposes and is not medical advice. Statements about these supplements have not been evaluated by the FDA, and no product here is intended to diagnose, treat, cure or prevent any disease. Always consult a qualified healthcare professional before starting any supplement, especially if you are pregnant, nursing, taking medication or have a medical condition.